The non-axismetrical caisson may be eccentric in long distance floating transport.Based on hydrostatic pressure distribution of eccentric caisson，the calculation method of initial inclination angle is deduced by using the water pressure moment balance method，and the ratio of draft to width and eccentric distance to width are taken as variables to evaluate the effect of boundary dimension and distribution of mass on initial inclination angle.Finally，according to the geometric relationship between gravity and buoyancy of caisson，metacentric radius of eccentric caisson is calculated，and the influence law of initial inclination angle and ratio of width to draft on metacentric radius is summarized.This study provides a method for calculating the floating stability of caisson floating，which can provide a basis for evaluating the safety reserve of long distance floating transport.