The large diameter and big slope(Slope 1  6)PHC pipe pile on land is designed to have pile foundation with high density.The construction accuracy of sinking pile is high and difficult.Aiming at these problems,the engineering piling test and static load experiment are carried out based on one dredged harbor basin project.In order to reduce the adverse effect of squeezing soil due to pile sinking on pile foundation,it is adopted the construction of first sinking the inclined pile and then the vertical pile as well as conducting pile driving from middle to both sides symmetrically.At the meanwhile,the construction measures avoiding bumping pile and difficult piling are taken.Results show that the construction scheme is feasible,pile driving effect is good,and the test results of pile foundation are Ⅰ type of pile.The construction scheme can provide the reference for the PHC pipe pile design and construction of similar projects.